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In college, Dr. Johnston was drawn to immunology and considered a career as an immunologist. After spending time working in the lab, he realized that it would be much more exciting to treat people with allergic and immune disorders, especially since he grew up having both allergic rhinitis and asthma. Dr. Johnston was attracted to Osteopathic medicine because its core principles focus on the body’s ability to function as a whole and heal itself, a key role of the immune system.
Dr. Johnston is a fellow of the American College of Allergy, Asthma, and Immunology and the American Academy of Allergy, Asthma, and Immunology (AAAAI). He has served as chair of the Urticaria/Angioedema subcommittee and the Allergic Skin Disease committee for the AAAAI. He is an Assistant Professor of Medicine at the Edward Via School of Osteopathic Medicine in Spartanburg, SC. and is the featured allergist on the Allergy and Asthma Foundation of America’s “Ask the Allergist” website.
He is very passionate about food allergy, which stems from having a daughter with peanut allergy. He was very excited to participate as a principal investigator and author of the Palisades peanut desensitization study, which led to the FDA approval of a treatment to desensitize children with peanut allergy. In addition, Dr. Johnston has expertise in angioedema and eosinophilic esophagitis (EoE) and has served as principal investigator for novel and future therapies for these disorders. He has lectured at national and international medical conferences and has publications in several medical journals including Clinical Immunology, WAO Journal, Journal of Allergy, Asthma, and Immunology, JAMA, and the New England Journal of Medicine.
Dr. Johnston continually learns from his patients and is a strong advocate of shared decision-making in medicine. When not working, he enjoys watching soccer, traveling with his wife and two daughters, and making Neapolitan pizza.
Always passionate about professional research, Dr. Johnston has more than 100 publications, including articles, book chapters and scientific abstracts. A selection of these publications are listed below:
Banerji A, Anderson J, Johnston DT. Optimal management of hereditary angioedema: shared decision-making. Journal of Asthma and Allergy In Press 2021
Johnston DT, Li HH, Craig TJ et al. Androgen use in hereditary angioedema: A critical appraisal and approaches to transitioning from androgens to other therapies. Allergy Asthma Proc 2021;42:1-8
Johnston DT. Examining unmet needs in the management of eosinophilic esophagitis. Am J Manag Care. 2021 In-press
Johnston DT, Busse PJ, Riedl MA et al. Effectiveness of lanadelumab for preventing hereditary angioedema attacks: subgroup analyses from the HELP Study. Clin Exp Allergy. 2021 Jun 24
Ma C, Schoepfer AM, Safroneeva E; COREOS Collaborators. Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS): An International Multidisciplinary Consensus. Gastroenterology. 2021 May 19:S0016-5085.
Wedner HJ, Aygören-Pürsün E, Bernstein J, Craig T, Gower R, Jacobs JS, Johnston DT, Lumry W, Zuraw BL, Best JM, Iocca HA, Murray SC, Desai B, Nagy E, Sheridan WP, Kiani-Alikhan S. Randomized Trial of the Efficacy and Safety of Berotralstat (BCX7353) as an Oral Prophylactic Therapy for Hereditary Angioedema: Results of APeX-2 Through 48 Weeks (Part 2). J Allergy Clin Immunol Pract. 2021 Apr 15:S2213-2198(21)00445-1
Banerji A, Anderson J, Johnston DT. Optimal management of hereditary angioedema: shared decision-making. J Asthma Allergy. 2021;14:119-125.
Zuraw B, Lumry WR, Johnston DT et al. Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: a randomized, double-blind, placebo-controlled phase 3 trial. J Allergy Clin Immunol. Published online OCT 23, 2020
Johnston DT, Smith RC. Hereditary Angioedema: Special considerations in children. Allergy Asthma Proc 2020;41:S43-46
Effect of Lanadelumab Compared With Placebo on Prevention of Hereditary Angioedema Attacks: A Randomized Clinical Trial. JAMA. 2018 Nov 27;320(20):2108-2121.
The PALISADE Group of Clinical Investigators. AR101 oral immunotherapy for peanut allergy. N Engl J Med. 2018 Nov 22;379:1991-2001.
Gower RG, Busse PJ, Aygören-Pürsün E, Barakat AJ, Caballero T, Davis-Lorton M, Farkas H, Hurewitz DS, Jacobs JS, Johnston DT, Lumry W, Maurer M. Hereditary Angioedema Caused By C1-Esterase Inhibitor Deficiency: A Literature-Based Analysis and Clinical Commentary on Prophylaxis Treatment Strategies. WAO Journal. 2011;4:S9-S21.
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